Table 1. Complete quantitative histomorphometry in trabecular bone in the distal femur at 8 weeks of agea.
| Quantitative histomorphometry parameters | Nrf2+/+ | Nrf2−/− |
| Dynamic parameters | ||
| Mineralizing surface/bone surface (MS/BS; %) | 6.36±0.69 | 5.96±2.28 |
| Mineral apposition rate (MAR; μm·d−1) | 1.81±0.28 | 1.07±0.22* |
| Bone formation rate/bone surface(BFR/BS; mm3·cm−2 per year) | 26.55±13.4 | 15.03±11.5 |
| Mineralization lag time (Mlt; day) | 2.25±1.06 | 1.97±0.6 |
| Formation parameters | ||
| Osteoid volume/bone volume (OV/BV; %) | 2.96±0.69 | 1.16±0.32* |
| Osteoid surface/bone surface (OS/BS; %) | 9.00±1.91 | 4.60±1.07* |
| Osteoid thickness (O.Th; μm) | 3.87±0.22 | 2.69±0.34* |
| Osteoblast surface/bone surface (Ob.S/BS; %) | 2.52±0.84 | 2.07±0.58 |
| Osteoblast number/bone length (Ob.N/BLength; no. per 100 μm) | 1.96±0.61 | 1.72±0.47 |
| Osteoblast number/tissue area (Ob.N/ TA; no. per mm2) | 9.05±2.91 | 7.47±2.19 |
| Resorption parameters | ||
| Erosion surface/bone surface (ES/BS; %) | 2.00±0.46 | 2.47±0.79 |
| Osteoclast surface/bone surface (OC.S/BS; % ) | 2.00±0.39 | 2.17±0.66 |
| Osteoclast number/bone length (Oc.N/BLength; no. per 100 μm) | 0.63±0.11 | 0.78±0.23 |
| Osteoclast number/tissue area (Oc.N/TA; no. per mm2) | 3.03±0.62 | 3.47±1.19 |
a
Values are shown as mean±s.e.
*
Statistically significant difference from control, P<0.05.