Table 2.
Correlations among several FilGAP-related markers investigated in malignant lymphoma
| FilGAP r (P) | FLNa r (P) | Integrin β2 r (P) | ECT2 r (P) | |
|---|---|---|---|---|
| FL | ||||
| Filamin A | 0.27 (0.03) | NE | NE | NE |
| Integrin β2 | 0.03 (0.95) | 0.24 (0.07) | NE | NE |
| ECT2 | 0.04 (0.78) | −0.2 (0.12) | 0.12 (0.38) | NE |
| Rac1 | 0.56 (<0.01) | 0.57 (<0.01) | −0.12 (0.61) | −0.05 (0.58) |
| DLBCL (GCB) | ||||
| Filamin A | 0.24 (0.24) | NE | NE | NE |
| Integrin β2 | −0.12 (0.57) | −0.13 (0.43) | NE | NE |
| ECT2 | 0.4 (0.02) | 0.19 (0.27) | 0.13 (0.45) | NE |
| Rac1 | 0.79 (0.03) | 0.67 (0.08) | −0.24 (0.31) | 0.6 (0.2) |
| DLBCL (non-GCB) | ||||
| Filamin A | −0.08 (0.27) | NE | NE | NE |
| Integrin β2 | −0.2 (0.34) | 0.03 (0.86) | NE | NE |
| ECT2 | 0.11 (0.25) | −0.09 (0.59) | 0.18 (0.25) | NE |
| Rac1 | 0.58 (0.04) | −0.07 (0.98) | −0.17 (0.67) | 0.39 (0.31) |
| PTCL | ||||
| Filamin A | 0.27 (0.22) | NE | NE | NE |
| Integrin β2 | −0.11 (0.67) | 0.14 (0.59) | NE | NE |
| ECT2 | 0.27 (0.13) | −0.21 (0.35) | 0.37 (0.18) | NE |
| Rac1 | −0.13 (0.26) | 0.14 (0.83) | −0.19 (0.69) | −0.66 (<0.01) |
FilGAP, a Rho GTPase-activating protein (GAP); FLNa, filamin A; r, Pearson's correlation coefficient; FL, follicular lymphoma; DLBCL, diffuse large B-cell lymphoma; ECT2, epithelial cell transforming factor 2; GCB, germinal center B-cell-like; PTCL, peripheral T-cell lymphoma; NE, not examined.