Table 1. SPR analysis of monoclonal antibody binding to gp41 oligomers.

Immunogen (antibody)	Kon (1/Ms)	Koff (1/s)	KD (M)
FDA18 (2F5)	4.73e3	8.34e-5	1.76e-8
FDA18 (4E10)	3.9e3	8.24e-4	2.12e-7
FDA13 (2F5)	1.35e5	6.69e-5	4.95e-10
FDA13 (4E10)	1.17e3	6.11e-4	5.24e-7
FDA20 (2F5)	9.67e3	9.21e-4	9.52e-8
FDA20 (4E10)	1.18e3	1.04e-4	8.81e-8
FDA26 (2F5)	2.31e4	9.03e-4	3.91e-8
FDA26 (4E10)	1.44e4	1.95e-3	1.35e-7
FDA21 (2F5)	2.26e4	4.2e-4	1.86e-8
FDA21 (4E10)	1.87e4	4.57e-3	2.44e-7
FDAB4 (2F5)	1.35e4	6.37e-4	4.73e-8
FDAB4 (4E10)	7.47e3	2.33e-3	3.12e-7
FDA22 (2F5)	2.19e4	3.56e-4	1.68e-8
FDA22 (4E10)	6.54e3	5.28e-4	8.08e-8