Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2015 Jun 18;15:57. doi: 10.1186/s12896-015-0146-8

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© Droste et al. 2015

This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

PMC Copyright notice

Influence of scFv-Fc antibodies (Yumabs) on Aβ42 fibrillogenesis. Left: 5 μM Aβ42 monomers were incubated with 2 μM (red), 1 μM (blue), 0.5 μM (green) or 0 μM (black) of scFv-Fc antibodies at 37°C under constant agitation of 300 rpm, ThT fluorescence was monitored over a time course of 96 h. All measurements were carried out in triplicates, the error bars represent the respective standard deviation. Right: representative TEM images of the fibrils formed from of 5 μM Aβ42 monomer after 96 h incubation in the presence of 2 μM scFv-Fc antibody, scale bar corresponds to 400 nm.