Table 3.
Immunohistochemical staining results
| COO | bcl2 | c-myc | CD5 | CD95 | CD168 | Cyclin E | FOXP1 | pSTAT3 | EBER | |
|---|---|---|---|---|---|---|---|---|---|---|
| Evaluable cases | 123 | 123 | 123 | 123 | 123 | 123 | 123 | 123 | 123 | 123 |
| Mean % of stained cells ± SD | na | 34 ± 38 | 32 ± 26 | 2 ± 14 | 32 ± 42 | 4 ± 9 | 8 ± 13 | 31 ± 38 | 19 ± 27 | na |
| N (%) above cutoff | na | 34 (28) | 44 (36) | 4 (3) | 60 (48) | 38 (31) | 30 (24) | 44 (36) | 44 (36) | 2 (1.5) |
| Mean % of stained cells ± SD in positive cases | na | 94 ± 10 | 61 ± 20 | 72 ± 27 | 65 ± 38 | 13 ± 13 | 26 ± 13 | 79 ± 17 | 49 ± 26 | 33 ± 25 |
| Germinal center B cell (GCB) like, N (%) | 42 (34) | 11 (32)a | 16 (36)a | 1 (25)a | 22 (37)a | 18 (47)a | 11 (37)a | 8 (18)a | 17 (39)a | 1 (50)a |
Except for FOXP1, which was of prognostic significance as an isolated marker, all other relevant proteins for cell of origin (COO) classification according to the Tally algorithm are summarized within the COO column
na not applicable
aGCB out of the positive cases