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Pathological changes of hippocampus detected in each group. a In the sham-operated group, hippocampal neurons appeared almost normal. b In the CLP-3 h group, hippocampal cells showed slight edema. c In the CLP-12 h group, hippocampal cells were arranged in disorder; the structure was unclear; and neurons appeared to have experienced acute traumatic change. Original magnification: ×400. CLP cecal ligation and puncture
