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Gene expression alterations in S. pneumoniae tetracycline-resistant mutants. Gene expression was compared between S. pneumoniae R6 WT and R6M1TC-5 or R6M2TC-4 by RNA-seq. Results for R6M2TC-4 are shown. The dots represent the 2043 genes from the S. pneumoniae R6 genome sorted in numerical order on the abscissa. Black dots represent overexpressed and down-regulated genes (P ≤ 0.01) and grey dots represent not significantly altered genes.
