. Author manuscript; available in PMC: 2016 May 1.

Published in final edited form as: Int J Oral Maxillofac Implants. 2015 May-Jun;30(3):707–714.

Table I.

Biochemical and biometric measurements of diabetic and non-diabetic animals treated with rhBMP-2 and control treatments obtained on experimental day 33

Parameter	Non-diabetic	Diabetic
Blood glucose (mg/dl)	126.2 ± 11.1	498.3 ± 64.2^*
GHb A1c (ng/ml)	6.58 ± 0.7	14.6 ± 1.6^*
Food (g/day/animal)	6.1 ± 1.9	12.1 ± 3.1^*
Weight (g)	29.3 ± 0.4	26.12 ± 0.9^*

Measurements were performed on experimental day 33. Results were presented as means +/− standard deviation. Data from 32 diabetic and 32 non-diabetic animals are presented. Glucose and Glycated hemoglobin levels were obtained from whole blood preparations. Diabetic animals are hyperglycemic. Significantly elevated GHb A1c levels documented sustained hyperglycemia in diabetic animals. Diabetic animals exhibited reduced body weight, despite being significantly hyperphagic as expected and consistent with previous findings (8).

(* p <0.05; un-paired t-test or Mann-Whitney).