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. Author manuscript; available in PMC: 2016 Jan 1.
Published in final edited form as: Thorax. 2014 Sep 12;70(1):48–56. doi: 10.1136/thoraxjnl-2013-204596

Figure 2.

Figure 2

Spatial heterogeneity of pathophysiology in a single representative IPF biopsy.

A) Low-power magnification of an H&E-stained paraffin section of explanted lung tissue from an IPF patient. Pleural surface is at lower right. b, c, and d indicate regions shown at higher magnification in: (B), normal-appearing alveolar structure, (C) transition zone underlying normal-appearing parenchyma with thickened alveolar walls, (D) advanced scar tissue with microscopic honeycombing and bronchiolization.