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. Author manuscript; available in PMC: 2015 Jun 19.
Published in final edited form as: Cancer Res. 2008 Oct 1;68(19):8004–8013. doi: 10.1158/0008-5472.CAN-08-0280

Table 1.

IC50 values of PQIP (P) and Tarceva (T) and P+T at constant ratio in FET, CBS and GEO cells

IC50 value* PQIP (μM) Tarceva (μM)
Treatment FET CBS GEO FET CBS GEO
PQIP single drug 0.28 ± 0.14 0.64 ± 0.12 0.24 ± 0.14 NA NA NA
Tarceva single drug NA NA NA 3.33 ± 0.15 9.91 ± 1.29 0.99 ± 0.10
P+T (1:9 for FET, 1:10 for CBS, 1:2 for GEO) 0.025 ± 0.005 0.081 ± 0.025 0.044 ± 0.029 0.223 ± 0.048 0.806 ± 0.255 0.089 ± 0.057
*

IC50 values were determined from MTT data after 72 hours drug treatment by Calcusyn software. Representative data of two repeated experiments were shown here.