Table 3. Estimated per cent changes* (95% CIs) in heart rate variability and heart rate associated with an IQR increase in baseline blood marker.
| IQR | SDNN % Change (95% CI) |
r-MSSD % Change (95% CI) |
PNN50 % Change (95% CI) |
HF % Change (95% CI) |
LF % Change (95% CI) |
Heart rate % Change (95% CI) |
|
|---|---|---|---|---|---|---|---|
| CRP | 5.8 mg/l | −8.0 (−17.9 to 3.0) | −19.1 (−38.0 to 5.5) | −22.4 (−62.1 to 58.7) | −32.2 (−53.2 to −1.8) | −32.6 (−52.2 to −5.0) | 0.8 (−4.8 to 6.8) |
| Fibrinogen | 1.2 g/l | −9.1 (−22.0 to 6.1) | −29.4 (−50.0 to −0.4) | −54.1 (−81.3 to 13.1) | −34.2 (−60.5 to 9.5) | −22.9 (−53.1 to 26.8) | 3.9 (−3.7 to 12.0) |
| IL-6 | 2.4 pg/ml | 0.65 (−7.3 to 9.3) | −7.1 (−22.9 to 12.0) | 4.1 (−36.2 to 70.1) | −2.4 (−25.7 to 28.3) | −5.0 (−26.5 to 22.7) | −1.5 (−5.2 to 2.4) |
| sICAM-1 | 89 ng/ml | 2.8 (−6.0 to 12.3) | −9.3 (−25.6 to 10.5) | 10.4 (−34.5 to 85.8) | −14.4 (−35.9 to 14.2) | −11.5 (−32.7 to 16.3) | −1.0 (−5.0 to 3.1] |
| WBC | 1.3 109/I | −0.07 (−9.0 to 9.7) | 0.5 (−19.1 to 24.7) | 3.8 (−40.7 to 81.7) | −13.4 (−36.0 to 17.2) | −15.7 (−36.4 to 11.7) | 2.4 (−2.0 to 6.9) |
| Platelets | 108 109/l | −15.1 (−27.6 to −0.4) | −41.6 (−58.4 to −18.1) | −74.2 (−89.2 to −38.1) | −61.5 (−74.6 to −41.6) | −54.5 (−70.6 to −29.6) | 6.4 (−1.9 to 15.4) |
*
Adjusted for age, gender, race, BMI, season, time of day and apparent temperature.
CRP, C-reactive protein; HF, high frequency power; IL-6, interleukin-6; LF, low frequency power; PNN50, the per cent of RR intervals more than 50 msec different from the prior interval; r-MSSD, the mean square of differences between adjacent RR intervals; SDNN, SD of normal RR intervals; sICAM-1, soluble inter-cellular adhesion molecule 1; WBC, white blood cell count.