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. Author manuscript; available in PMC: 2015 Jun 19.
Published in final edited form as: Psychopharmacology (Berl). 2012 Sep 14;225(3):733–742. doi: 10.1007/s00213-012-2862-2

Figure 3.

Figure 3

Effects of pretreatments with methylphenidate or N-substituted BZT analogs (JHW 007, AHN 1-055 and AHN 2-005) on spontaneous locomotor activity and stereotyped behavior in rats with cocaine injections. Cocaine (10-56 mg/kg), saline, methylphenidate (1.0-30 mg/kg), JHW 007 (10 and 17 mg/kg), AHN 1-055 (3.0 and 10 mg/kg), and AHN 2-005 (3.0 and 10 mg/kg) were administered intraperitoneally respectively five, five, five, 180, 90, and 90 min before sessions. Each point represents the mean ±SEM (N=6). Panel A-D. Effects on spontaneous locomotor activity. Ordinates: Activity counts (0-30 min). Abscissae: cocaine dose in mg/kg/inj. Veh: vehicle. Panel E-H. Effects on stereotypy scores. Ordinates: Stereotypy scores (0-30 min). Abscissae: cocaine dose in mg/kg/inj. Veh: vehicle.