Table 3.
Baseline and peri-operative characteristics of the control and dexmedetomidine (DEX) groups after propensity score matching
| Control (n = 468) | DEX (n = 468) | p-Value* | |
|---|---|---|---|
| Age at surgery (days) | 180 (108 – 957) | 782 (175 – 1793) | <0.001‡ |
| Gender | |||
| Male | 52% (244) | 51% (239) | 0.79† |
| Female | 48% (224) | 49% (229) | |
| BSA | 0.35 (0.28 – 0.55) | 0.51(0.33 – 0.69) | <0.001‡ |
| RACHS-1 Category | 2 (2 – 3) | 3 (2 – 3) | 0.59‡ |
| Race | |||
| White | 84% (394) | 84% (393) | >0.99† |
| Other | 16% (74) | 16% (75) | |
| CPB Time (min) | 95 (61 – 130) | 94 (63 – 133) | 0.32‡ |
| Cross Clamp Time (min) | 33 (0 – 57) | 30.5 (2 – 56) | 0.93‡ |
| Labs upon PCICU admission | |||
| pH | 7.37 (7.32 – 7.41) | 7.36 (7.31 – 7.41) | 0.81‡ |
| pCO2 | 43 (38 – 49) | 43 (38 – 49) | 0.26‡ |
| pO2 | 97 (50 – 167) | 99 (58 – 166) | 0.90‡ |
| Base Excess | −0.7 (−3.5 – 1.7) | −1.4 (−3.9 – 1.2) | 0.16‡ |
| Lactate | 1.4 (1.1 – 2.1) | 1.4 (1.0 – 2.0) | 0.09‡ |
| Hematocrit | 38 (34 – 43) | 38 (34 – 42) | 0.33‡ |
| Potassium | 3.5 (3.1 – 3.9) | 3.6 (3.2 – 3.9) | 0.20‡ |
| Ionized Calcium | 5.4 (4.9 – 6.0) | 5.4 (4.9 – 6.0) | 0.89‡ |
| Infusions upon PCICU admission | |||
| Calcium Chloride | 7% (31) | 5% (23) | 0.33† |
| Dopamine | 14% (66) | 16% (73) | 0.58† |
| Epinephrine | 15% (68) | 14% (67) | >0.99† |
| Milrinone | 66% (308) | 63% (297) | 0.50† |
| Nipride | 35% (164) | 35% (166) | 0.95† |
| Aminocaproic Acid | 27% (128) | 35% (166) | 0.005† |
Values are represented as median (interquartile range) or % (n)
BSA: body surface area; RACHS-1: Risk Adjustment for Congenital Heart Surgery version 1; CPB: cardiopulmonary bypass; PCICU: pediatric cardiac intensive care unit
*
p-Value represents the relationship between the control and DEX groups
†
McNemar’s test
‡
Wilcoxon signed-rank test