. Author manuscript; available in PMC: 2016 Jun 1.

Published in final edited form as: Circ Arrhythm Electrophysiol. 2015 Apr 15;8(3):643–650. doi: 10.1161/CIRCEP.114.002301

Table 7.

Logistic regression analysis of total dexmedetomidine (DEX) dose (mcg/kg) in the first 24 post-operative hours and total DEX dose (mcg/kg) over the entire post-operative course, adjusting for potential confounders

	Odds Ratio (95% CI) First 24 Post-Operative Hours^*	Odds Ratio (95% CI) Entire Post-Operative Course^*
One or More Arrhythmia	0.96 (0.74 – 1.24)	1.02 (1.00 – 1.05)
Tachyarrhythmia	0.77 (0.57 – 1.03)	1.01 (0.98 – 1.04)
Tachyarrhythmia Receiving Intervention	0.98 (0.68 – 1.41)	1.03 (1.00 – 1.06)
Bradyarrhythmia	1.00 (0.73 – 1.38)	1.04 (1.01 – 1.07)^‡
Bradyarrhythmia Receiving Intervention^†	1.15 (0.79 – 1.67)	1.05 (1.01 – 1.08)^‡

Expressed as the odds ratio (95% confidence interval of the odds ratio) per 10 unit increase in dexmedetomidine dose (mcg/kg)

^†

Due to number of events, nine variables were chosen for inclusion (age, cardiopulmonary bypass time, RACHS-1 category, pH, lactate, milrinone, epinephrine, calcium chloride, hematocrit)

^‡

Indicates a p-value <0.05