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. Author manuscript; available in PMC: 2017 May 1.
Published in final edited form as: Head Neck. 2015 May 17;38(5):700–706. doi: 10.1002/hed.23944

Table 4.

Incidence of Postoperative Complications among Head and Neck Cancer Surgical Patients by Urinary Cotinine Level

All Participants (N=88) Negative Cotinineb (N=50) Positive Cotinine (N=38) p- valuea
N % N %
Any complication 37 (42.1%) 19 38.0 18 47.4 0.39
 Low acuity (N=25) 4 (16.0%) 3 21.4 (3/14) 1 9.1 (1/11) 0.60
 High acuity (N=63) 33 (52.4%) 16 44.4 (16/36) 17 63.0 (17/27) 0.20
Vascular 3 (3.4%) 3 6.0 0 0.0 0.26
Pulmonary 11 (12.5%) 4 8.0 7 18.4 0.20
Acute blood loss anemia 12 (13.6%) 4 8.0 8 21.1 0.12
Wound 16 (18.2%) 9 18.0 7 18.4 1.00
 Low acuity (N=25) 1 (4.0%) 1 7.1 (1/14) 0 0.0 1.00
 High acuity (N=63) 15 (23.8%) 8 22.2 (8/36) 7 25.9 (7/27) 0.77
Ethanol withdrawal 4 (4.6%) 1 2.0 3 7.9 0.31
Other complications 7 (8.0%) 4 8.0 3 7.9 1.00
a

From Fisher’s exact test;

b

Negative cotinine was considered test result <3 using NicAlert®