Table 3.

Laboratory features of cefazolin induced liver injury

Feature	Median	Range
Time from administration to laboratory abnormalities (days)	21	6–29
ALT (U/L), initial	380	135–769
AST (U/L), initial	189	47–623
Alkaline phosphatase (U/L), initial	360	170–1457
Bilirubin (mg/dL), initial	5.3	1.2 – 14.9
INR, initial	1.0	0.8–1.2
R value, initial	1.8	0.4 – 8.8
ALT (U/L), peak	409	135–1233
AST (U/L), peak	191	65–654
Alkaline phosphatase (U/L), peak	435	227–1527
Bilirubin (mg/dL), peak	9.8	1.9–18.8
INR, peak	1.1	1.0–2.0
Eosinophilia (no, % and count/µL)	5 (26%)	533 – 3400

R value = ratio of the serum ALT to alkaline phosphatase (both expressed as multiples of the ULN)