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. 2015 Jun 18;10(6):e0129881. doi: 10.1371/journal.pone.0129881

Fig 5. Reduction of damaged neurons and glial scar in the perihematomal areas.

Fig 5

(A) Representative Nissl staining for each group (Sham; PBS; PBS+iPSCs) at day 42 post ICH. (B) Histograms show changes in percentages of Nissl+ cells at day 42 post ICH. Data are mean values with SEM. There was less damage to Nissl bodies and nucleus within neural cells in the iPSC group compared with that in the PBS group, while it has hardly any damage to Nissl bodies and nucleus in Sham group (A and B; n = 6/group; &&P<0.01 compared with Sham group; &P<0.05 compared with Sham group; **P<0.01 compared with PBS group. The # signs indicate hematomal areas. Bar=20 μm). (C) Representative immunostaining for GFAP+ cells of one representative rat of 3 groups (Sham; PBS; PBS+iPSCs) at day 42 post ICH. (D) Histograms show changes in the thickness of glial scar through measuring GFAP+ cells at day 42 post ICH. Shown are the mean values with SEM. The thickness of glial scar in iPSC group is less than that of PBS group (C and D; n = 6/group; **P<0.01 compared with PBS group. The # signs indicate hematomal areas. Bar=50 μm).