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. 2015 Jun 18;10(6):e0130322. doi: 10.1371/journal.pone.0130322

Fig 5. TSH/M22-induced TNFα protein production in fibrocytes is attenuated by TMB, a human anti-IGF-1R monoclonal antibody.

Fig 5

Both circulating and cultured fibrocytes were pretreated with TMB, prior to TSH or M22 stimulation. TMB decreases TSH/M22-induced TNFα protein production in healthy (from MFI value of 2.92 to 1.91 for TSH; and from 1.67 to 1.12 for M22) (A, B) and GD circulating fibrocytes (from MFI value of 1.82 to 1.23 for TSH; and from 1.66 to 1.19 for M22) (C, D).