Table 2. Minimum inhibitory concentration (MIC) and minimum bactericidal concentration (MBC) of thiazole compounds 1–6, clindamycin, and rifampicin (triplicate samples) against nine methicillin-sensitive Staphylococcus pseudintermedius and six methicillin-resistant Staphylococcus pseudintermedius isolates.

	Methicillin-sensitive Staphylococcus pseudintermedius				Methicillin-resistant Staphylococcus pseudintermedius
Compound Number/Antibiotic	MIC50 1 (μg/mL)	MIC Range(μg/mL)	MBC50 2 (μg/mL)	MBC Range(μg/mL)	MIC50 (μg/mL)	MIC Range(μg/mL)	MBC50(μg/mL)	MBC Range (μg/mL)
1	0.35	0.17–1.38	0.46	0.17–2.77	0.69	0.35–1.38	0.92	0.35–1.38
2	0.30	0.15–0.61	0.61	0.15–2.42	0.46	0.15–0.61	0.61	0.30–0.81
3	0.71	0.18–0.94	0.71	0.18–1.41	0.48	0.18–1.41	0.71	0.18–1.41
4	0.73	0.18–2.94	1.10	0.18–2.94	1.47	0.37–1.47	1.47	0.31–2.94
5	0.42	0.21–1.67	0.42	0.21–6.67	0.42	0.21–1.67	0.42	0.21–3.34
6	0.80	0.20–1.60	1.06	0.20–3.19	0.40	0.20–1.60	0.80	0.20–1.60
Clindamycin	0.48	0.24–61.37	0.48	0.24- >61.37	0.48	0.24- >30.69	30.69	0.24- >61.37
Rifampicin	<0.41	<0.41	<0.41	<0.41	<0.41	<0.41	<0.41	<0.41

¹MIC₅₀ corresponds to the lowest concentration of each test agent that inhibited growth in 50% of bacterial isolates screened.

²MBC₅₀ corresponds to the lowest concentration of each test agent that killed 50% of bacterial isolates screened.