FIGURE 1.

HCV proteins contain functional nuclear transport signals (NTSs). (A) A summary of HCV proteins binding to Kaps, as well as the sequences of identified NTSs. Basic residues within NLSs are in boldface; hydrophobic residues within NESs are underlined; the single letter amino acid code is used; *protein that can be detected within the host cell nucleus during viral infection. (B) Schematic representation of core and NS5A proteins, their functional domains as well as their NTSs and the Kap-binding sites.