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. 2015 Jun 19;6:299. doi: 10.3389/fimmu.2015.00299

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Copyright © 2015 Vu Manh, Elhmouzi-Younes, Urien, Ruscanu, Jouneau, Bourge, Moroldo, Foucras, Salmon, Marty, Quéré, Bertho, Boudinot, Dalod and Schwartz-Cornil.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Confirming homology assignment of sheep cDC1 and cDC2 candidates by unsupervised cross-species hierarchical clustering focused on cDC subsets. An unsupervised cross-species hierarchical clustering analysis was performed as described in Figure 5, but focused only on cDC subsets. The corresponding filtered dataset included 868 unique orthologous genes found regulated between cDC1 and cDC2 from human (Hs), mouse (Mm), and sheep (Oa). Pig cDC could not be included in this analysis due to the lack of data on proper pig cDC2.