Fig 4. The effect of LVFX on oxidative stress in influenza virus-infected mice.

The effect of LVFX on the accumulation of oxidative stress in the blood or lungs were determined (A) by measuring hydroperoxide levels (dROMs test) or (B) immunostaining for 8-OHdG (upper panel) and NO₂-Tyr (lower panel) level at the day 7 after influenza virus infection. The fluorescence intensity of (C) 8-OHdG and (D) NO₂-Tyr were quantified by the imageJ software. Each bar represents the mean ± SD (n = 5–9). **p<0.01, ***p<0.001 vs control.