Table 2.

Recommendation for the type of revascularization (CABG or PCI) in patients with SCAD and left main coronary artery disease with suitable anatomy and low predicted surgical mortality

	ESC GL 2014		ESC GL 2010		American societies’ GLc
	CABG	PCI	CABG	PCI	PCI
SYNTAX score ≤22	I B	I B	I A	IIa/b Ba	• IIa B—if low risk of PCI complications and significantly increased surgical risk (e.g., STS ≥5 %)
SYNTAX score 23–32	I B	IIa B	I A	IIb Bb	• IIb B—if low to intermediate risk of PCI complications and increased surgical risk (e.g., STS >2 %)
SYNTAX score >32	I B	III B	I A	III B	• III B—if unfavorable anatomy for PCI and good candidates for CABG

GL guidelines

^aIndication IIa B for left main lesion at ostium/shaft. Indication IIb B for left main lesion at distal bifurcation

^bIndication for left main disease associated to two- or three-vessel disease and a SYNTAX score ≤32

^cIndication to improve survival with revascularization as compared to medical therapy