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. 2015 Jun 18;53(7):2163–2171. doi: 10.1128/JCM.03467-14

TABLE 3.

Characteristics of isolates used for external validation

Resistance mechanism and variant Strain Species MIC range (mg/liter)
MS ratio
Imipenem Ertapenem Meropenem
ESBL VT43 K. pneumoniae 0.5 16 2 0.20
Porin defect VT12 E. coli 0.25 1.5 0.125 0.32
Cephalosporinase VT28 C. freundii 0.25 0.5 0.125 0.20
VT31 C. freundii >32 >32 12 0.11
VT10 E. aerogenes 0.19 0.19 0.064 0.22
VT24 E. cloacae 0.19 0.19 0.032 0.18
VT32 E. cloacae 0.125 0.38 0.047 0.25
VT37 E. cloacae 0.25 0.25 0.094 0.32
VT40 E. cloacae 0.25 0.5 0.047 0.11
VT4 E. cloacae 0.19 0.38 0.064 0.27
VT20 E. cloacae 0.25 0.5 0.125 0.17
VT22 E. cloacae 1.5 1.5 0.5 0.17
VT11 E. cloacae 4 >32 6 0.20
VT14 K. oxytoca 0.19 0.064 0.047 0.34
VT1 E. cloacae 0.25 0.75 0.125 0.25
Cephalosporinase + ESBL VT26 E. cloacae 0.38 1 0.125 0.13
VT7 E. cloacae 1.5 0.5 0.19 0.38
VT42 E. cloacae 3 2 0.5 0.15
KPC
    KPC-2 VT23 E. cloacae 3 6 2 0.98
    KPC-2 VT29 E. coli 0.5 8 1 0.97
    KPC-2 VT30 K. pneumoniae 1 8 1 0.99
    KPC-2 VT17 K. pneumoniae 6 >32 4 1.00
    KPC-2 VT25 K. pneumoniae 1.5 4 1.5 0.98
    KPC-2 VT38 K. pneumoniae 2 24 2 1.00
    KPC-2 VT35 K. pneumoniae 12 12 16 1.00
    KPC-2 VT41 K. pneumoniae >32 >32 >32 1.00
    KPC-2 VT36 S. marcescens >32 >32 >32 0.99
NDM
    NDM-1 VT6 E. coli 0.75 2 0.75 1.00
    NDM-1 VT27 E. coli 8 8 32 0.98
    NDM-4 VT3 E. coli 0.15 >32 8 0.99
    NDM-5 VT15 E. coli 2 >32 4 1.00
    NDM-7 VT9 E. coli 2 >32 6 1.00
OXA-48 group
    OXA-181 VT13 E. coli 0.25 1 0.125 0.98
    OXA-181 VT44 E. coli 0.38 1.5 0.38 1.00
    OXA-48 VT2 E. coli 0.38 0.5 0.19 1.00
    OXA-48 VT5 E. coli 0.25 0.5 0.19 1.00
    OXA-48 VT18 E. coli 0.25 0.5 0.25 0.98
    OXA-48 VT33 E. coli 0.38 0.5 0.25 0.95
    OXA-48 VT34 E. coli 0.38 1 0.25 0.99
    OXA-48 VT16 K. pneumoniae 0.25 1 0.25 1.00
    OXA-48 VT8 K. pneumoniae 0.38 1.5 0.38 1.00
    OXA-48 VT39 K. pneumoniae 1 1.5 0.5 1.00
    OXA-48 VT21 K. pneumoniae 1.5 >32 4 1.00