TABLE 1.
Clinical isolates and laboratory reference strains used to test Hib/non-Hib classification
| Isolate | Capsular type | Location | Yr | Site of isolation |
|---|---|---|---|---|
| Hib | ||||
| Clinical isolates | ||||
| M58 | b | Malmö | 1997 | Blood |
| M61a | b | Malmö | 1997 | Blood |
| KR181a | b | Stockholm | 1998 | CSFb |
| G4a | b | Gothenburg | 2002 | Blood |
| M41 | b | Malmö | 2004 | Blood |
| M35a | b | Malmö | 2004 | Blood |
| L40 | b | Lund | 2004 | Blood |
| L2a | b | Lund | 2004 | Blood |
| KR196 | b | Stockholm | 2004 | Blood |
| KR192a | b | Stockholm | 2004 | Blood |
| M31 | b | Malmö | 2005 | Blood |
| L35a | b | Lund | 2005 | Blood |
| M66 | b | Malmö | 2006 | Blood |
| KR211 | b | Stockholm | 2006 | Blood |
| KR209a | b | Stockholm | 2006 | Blood |
| L58 | b | Lund | 2007 | Blood |
| L63a | b | Lund | 2008 | Blood |
| G32a | b | Gothenburg | 2008 | CSF |
| M7a | b | Malmö | 2009 | Blood |
| G26 | b | Gothenburg | 2009 | Blood |
| S86a | b | Stockholm | 2010 | Blood |
| S79 | b | Stockholm | 2010 | Blood |
| M81a | b | Malmö | 2010 | CSF |
| M75 | b | Malmö | 2010 | Blood |
| G74a | b | Gothenburg | 2010 | CSF |
| G72 | b | Gothenburg | 2010 | Blood |
| G67a | b | Gothenburg | 2010 | Blood |
| Laboratory reference strains | ||||
| CCUG 18095 (Eagan)a | b | Boston, MA | 1968 | CSF |
| MinnAa | b | Minneapolis, MN | 1979 | CSF |
| DL-42 | b | Dallas, TX | Before 1984 | Unknown |
| 850530a | b | Netherlands | 1985 | Unknown |
| HK 691a | b | Netherlands | Before 1985 | Unknown |
| HK 729 | b | United States | Before 1988 | CSF |
| Non-Hib | ||||
| Clinical isolates | ||||
| L59a | e | Lund | 2007 | Blood |
| KR228 | e | Stockholm | 2008 | Blood |
| KR236 | e | Stockholm | 2008 | CSF |
| KR138a | e | Unknown | Unknown | Unknown |
| KR147 | e | Unknown | Unknown | Unknown |
| KR569 | e | Malmö | 2009 | Tonsil |
| M63 | f | Malmö | 1997 | Blood |
| KR179a | f | Stockholm | 1998 | CSF |
| M54a | f | Malmö | 1999 | Blood |
| KR187 | f | Stockholm | 2000 | CSF |
| L45 | f | Lund | 2005 | Blood |
| L44 | f | Lund | 2005 | Blood |
| KR200 | f | Stockholm | 2005 | Blood |
| M65 | f | Malmö | 2006 | Blood |
| M29 | f | Malmö | 2006 | CSF |
| L11a | f | Lund | 2006 | Blood |
| KR210 | f | Stockholm | 2006 | Blood |
| L50a | f | Lund | 2007 | Blood |
| L19 | f | Lund | 2007 | Blood |
| L18 | f | Lund | 2007 | Blood |
| L16 | f | Lund | 2007 | Blood |
| M14 | f | Malmö | 2008 | Blood |
| M12 | f | Malmö | 2008 | Blood |
| M10a | f | Malmö | 2008 | Blood |
| L64 | f | Lund | 2008 | punctate |
| L22 | f | Lund | 2008 | Blood |
| L21 | f | Lund | 2008 | Blood |
| KR233a | f | Stockholm | 2008 | Blood |
| G34 | f | Gothenburg | 2008 | Blood |
| G22 | f | Gothenburg | 2008 | Blood |
| G20 | f | Gothenburg | 2008 | Blood |
| G19 | f | Gothenburg | 2008 | Blood |
| G18a | f | Gothenburg | 2008 | Blood |
| L29 | f | Lund | 2009 | Blood |
| L25 | f | Lund | 2009 | Blood |
| L24 | f | Lund | 2009 | Blood |
| S78 | f | Stockholm | 2010 | Blood |
| M60 | NTc | Malmö | 1997 | Blood |
| M59 | NT | Malmö | 1997 | Blood |
| KR170a | NT | Stockholm | 1998 | Blood |
| G1a | NT | Gothenburg | 1999 | Blood |
| KR183 | NT | Stockholm | 2000 | Blood |
| M51a | NT | Malmö | 2001 | CSF |
| G2a | NT | Gothenburg | 2001 | Blood |
| M45 | NT | Malmö | 2002 | Blood |
| M36 | NT | Malmö | 2004 | Blood |
| L3a | NT | Lund | 2004 | Blood |
| L17 | NT | Lund | 2004 | Blood |
| KR189 | NT | Stockholm | 2004 | Blood |
| KR201 | NT | Stockholm | 2005 | Blood |
| L9 | NT | Lund | 2006 | Blood |
| L8 | NT | Lund | 2006 | Blood |
| L48 | NT | Lund | 2006 | Blood |
| M23 | NT | Malmö | 2007 | Blood |
| M21 | NT | Malmö | 2007 | Blood |
| L61 | NT | Lund | 2007 | Blood |
| L57a | NT | Lund | 2007 | Blood |
| L56 | NT | Lund | 2007 | Blood |
| L55a | NT | Lund | 2007 | Blood |
| L20 | NT | Lund | 2007 | Blood |
| G14 | NT | Gothenburg | 2007 | Blood |
| M9 | NT | Malmö | 2008 | Blood |
| M13 | NT | Malmö | 2008 | Blood |
| KR223a | NT | Stockholm | 2008 | Blood |
| G17 | NT | Gothenburg | 2008 | Blood |
| M5 | NT | Malmö | 2009 | Blood |
| M4a | NT | Malmö | 2009 | Blood |
| M38 | NT | Malmö | 2009 | Blood |
| L26 | NT | Lund | 2009 | Blood |
| G40a | NT | Gothenburg | 2009 | Blood |
| Laboratory reference strains | ||||
| CCUG 6881a | a | Unknown | Before 1973 | Unknown |
| CCUG 7315 | a | United States | 1941 | Respiratory tract |
| CCUG 4851a | c | United States | 1942 | Sputum |
| CCUG 4852 | c | New York, NY | Before 1950 | CSF |
| NCTC 8470a | d | Netherlands | 1937 | Throat |
| CCUG 15521a | e | Unknown | Before 1984 | Unknown |
| CCUG 6877 | NT | United States | 1941 | Unknown |
a
To test reproducibility, extraction and MALDI-TOF MS measurements were also performed on a different instrument in a second laboratory.
b
CSF, cerebrospinal fluid.
c
NT, nontypeable.