TABLE 2.
Antimicrobial susceptibility patterns, genetic similarity, and carbapenemase content of the 6 KPC-2- and IMP-10-producing S. marcescens isolates
| Strain | PFGEc | MIC (mg/liter)a |
Gene location (kb)b |
||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| CAZ | CTX | CRO | FEP | ATM | IPM | MEM | ETP | AMK | GEN | CIP | LVX | TGC | PMB | blaKPC-2 | blaIMP-10 | ||
| 44 | A | >256 | >256 | >256 | >256 | >32 | >8 | >16 | >32 | 64 | >64 | 16 | 8 | 0.5 | >64 | P+ (100) | P− (150) |
| 1517 | A | >256 | >256 | >256 | 128 | >32 | >8 | >16 | >32 | 64 | 32 | 4 | 8 | 0.5 | >64 | P+ (100) | P− (150) |
| 2886 | A | >256 | >256 | >256 | >256 | >32 | >8 | >16 | >32 | 64 | >64 | 4 | 4 | 0.5 | >64 | P+ (100) | P− (150) |
| 4093 | A | >256 | >256 | >256 | >256 | >32 | >8 | >16 | >32 | 64 | >64 | 4 | 4 | 0.5 | >64 | P+ (100) | P− (150) |
| 7804 | A | 128 | >256 | 128 | >256 | >32 | >8 | >16 | >32 | 32 | 2 | 2 | 4 | 0.5 | >64 | P+ (100) | P− (150) |
| 37510 | A | >256 | >256 | >256 | >256 | >32 | >8 | >16 | >32 | 64 | 2 | 4 | 4 | 0.5 | >64 | P+ (100) | P− (150) |
a
CAZ, ceftazidime; CTX, cefotaxime; CRO, ceftriaxone; FEP, cefepime; ATM, aztreonam; IMP, imipenem; MEM, meropenem; ETP, ertapenem; AMK, amikacin; GEN, gentamicin; CIP, ciprofloxacin; LVX, levofloxacin; TGC, tigecycline; PMB, polymyxin B.
b
P+, conjugative plasmid; P−, nonconjugative plasmid.
c
A, genetic profiles.