Fig 7. Normal influenza-specific CD4⁺ T cell responses in oseltamivir-treated mice after secondary infection.

Mice were treated with PBS or oseltamivir and infected with influenza virus X31, then rested for 40 days. At this time point, mice were infected i.n. with 600 pfu of influenza PR8. At 8 days post-secondary infection, (A) MedLN and (B) BAL fluid were harvested and assessed for the total number of influenza IA^b- NP₃₁₁-specific CD4⁺ T cells by intracellular cytokine staining after ex vivo stimulation. These data represent 2 individual experiments with 4–5 mice per group. Error bars represent standard error of the mean. n.s., not significantly different.