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The impact of URI Knockdown on cell apoptosis induced by cisplatin. At 24 h after URI siRNA-A transfection, cells were exposed to cisplatin treatment for 48 h, and apoptosis assay was performed using the annexin V-FITC apoptosis detection kit. Cells in the right lower and right upper quadrants were considered as early and late apoptotic cells respectively. Cells down-regulation of URI have a higher apoptosis rate compared with control groups, **P<0.01.
