Figure 3.

Targeting DNMT3b inhibits tumor migration and invasion in vitro. (A and B) The cells that crossed the polycarbonate membrane of the Transwell chamber were stained with crystal violet to detect the migration of cells (magnification, ×100). *P<0.01 vs. mock control. (C and D) The glioma cells that crossed the Matrigel-coated polycarbonate membrane of the Transwell chamber were stained with crystal violet to detect the invasion of cells (magnification, ×200). *P<0.01. DNMT3b, DNA methyltransferase 3b; SiRNA, small interfering RNA.