Figure 1.

Effects of poly(lactic-co-glycolic acid)/poly(ethylene glycol) (PLGA/PEG) on bioluminescent monitoring of tumours Top: Xenograft of U87 human glioblastoma cell line grown in murine flank, excised, with bioluminescence measured before (A) and after (B) application of layer of PLGA/PEG, demonstrating reduction with coating of the biomaterial Bottom: Comparison of flux levels between coated and non-coated tumours demonstrating some reduction but to a lesser degree than with normal tissues (C), and bioluminescent imaging of mouse demonstrating tumour with resected core (arrow) (D)