Figure 2.

Poly(lactic-co-glycolic acid)/poly(ethylene glycol) (PLGA/PEG) application in vivo A: Excised U373 human glioblastoma murine flank xenograft 28 days following implantation, dissected in half, demonstrating central pale core of PLGA/PEG retained in surrounding tumour

B: Histology of tumour on left demonstrating PLGA/PEG matrix (*) closely opposed to tumour (#)

C: Ex vivo ovine model with cavity resection in brain, lined with pale PLGA/PEG sintered into place, and retaining shape and apposition to cavity walls

D: Scanning electron micrography of PLGA/PEG matrix microparticles