FIG 4.

The removal of multiple N-glycans in HeV G modulates viral entry, oligomerization, and glycoprotein incorporation into the virus. (A, B) Viral entry (A) and viral incorporation and oligomerization levels (B) of HeV G mutants were detected in experiments similar to those described in the legend to Fig. 3A and B. (C) Comparison of levels of incorporation of WT and mutant HeV and NiV G into virions and their effects on homologous F incorporation. The data shown in panel A are the average results ± SEM from at least three independent experiments. The results of one representative experiment out of three are shown in panels B and C. The percentages of F₁ cleavage were determined by densitometry.