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. 2015 Apr 14;9(6):2095–2103. doi: 10.3892/etm.2015.2422

Table II.

Information on the gene mutation status.

A, EGFR

Exon Amino acid change Nucleotide change Cases, n (%)
18 G719A 2156G>C 1 (1.28)
G719S 2155G>A 1 (1.28)
19 E746_A750del 2235–2249del 15 22 (28.2)
E746_A750del 2236–2250del 15 2 (2.56)
L747_P753>S 2240–2257del 18 5 (6.41)
E746_T751>A 2237–2251del 15 1 (1.28)
E746_T751>I 2235–2252>AATdel 18 1 (1.28)
L747_A750>P 2238–2248>GCdel 11 2 (2.56)
L747_A750>P 2239–2248>Cdel 10 1 (1.28)
L747_T751del 2239–2253del 15 1 (1.28)
L747_T751del 2240–2254del 15 1 (1.28)
L747_S752del 2239–2256del 18 1 (1.28)
L747_T751>P 2239–2251>Cdel 13 1 (1.28)
E746_S752>V 2237–2255>Tdel 19 1 (1.28)
20 S768I 2303G>T 1 (1.28)
V769_D770insASV 2307–2308insGACAACGTG 1 (1.28)
T790M 2369C>T 1 (1.28)
21 L858R 2573T>G 34 (43.6)

B, KRAS

Exon Amino acid change Nucleotide change Cases, n (%)

2 G12R 34G>C 2 (11.1)
G12C 34G>T 3 (16.7)
G12V 35G>T 5 (27.8)
G12D 35G>A 6 (33.3)
G13D 38G>A 2 (11.1)

EGFR, epidermal growth factor receptor; KRAS, Kirsten rat sarcoma virus.