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. 2015 Jun 19;5:11410. doi: 10.1038/srep11410

Figure 3. Impaired hematopoietic recovery of LPA4-deficient mice after 5-FU administration.

Figure 3

(A) Survival curves of LPA4-deficient and WT mice after 5-FU administration (n = 8). (B) Survival curves of LPA4-deficient and WT mice after X-ray irradiation (n = 7). (C,D) Kinetics of total BM cellularity (C) and HSPC number (D) in the BM after 5-FU administration (n = 6–11). (E,F) Survival curves of BM chimeric mice after 5-FU administration. (E) Analyses of Ly5.1 WT mice reconstituted with WT or LPA4-deficient BM (n = 9). (F) Analyses of WT and LPA4-deficient mice reconstituted with Ly5.1 WT BM (n = 8-9). *P < 0.05. **P < 0.01. ***P < 0.001.