Table 3.

White matter regions showing a significant correlation with neuropsychological test performance across subjects in both patient groups. A positive bootstrap ratio (BSR) denotes a positive correlation between white matter volume and cognitive test performance. BSRs are the ratio of a voxels weight divided by the bootstrap-derived standard error, and are equivalent to a z-score. Coordinates and BSRs are listed for the peak voxel of each cluster. Location labels are based on the major white matter tracts or the nearest gray matter region.

		White matter tract/nearest brain region	Cluster size (voxels)	X	Y	Z	BSR
Frontal
	R	Middle frontal region	39	43.5	15	51	−5.26
	R	Middle frontal region	77	28.5	7.5	58.5	−5.23
	R	Inferior frontal region	35	48	24	−13.5	−5.69
	L	Superior frontal region	20	−22.5	37.5	37.5	5.43
Temporal
	L	Inferior temporal region	20	−55.5	−61.5	−18	4.98
Parietal
	L	Precentral region	166	−60	3	27	−5.72
Occipital
	R	Primary visual region	30	6	−57	9	−5.40
Other
	L/R	Fornix	585	0	−19.5	13.5	6.38
	L	Fimbria	346	−34.5	−19.5	−15	6.13
	R	Posterior corona radiata	44	19.5	−31.5	37.5	4.69

BSR = bootstrap ratio.