Table 3.
Bivariate and multivariate analysis for patient related risk factors for any drug resistance among pulmonary TB patients attending two public hospitals in East Gojjam zone, northwest Ethiopia (n = 89)
| Characteristic | Any drug resistance | COR (95 % CI) | P-value | AOR (95 % CI) | p-value | |
|---|---|---|---|---|---|---|
| Yes, n (%) | No, n (%) | |||||
| Sex | ||||||
| Male | 13 (72.2) | 45 (63.4) | 1.52 (0.48-4.69) | 0.48 | ||
| Female | 5 (27.8) | 26 (36.6) | ||||
| HIV-status | ||||||
| HIV-positive | 6 (33.3) | 11 (15.5) | 2.72 (0.85-8.81) | 0.093 | 2.76 (0.72-10.54) | 0.14 |
| HIV-negative | 12 (66.7) | 60 (84.5) | ||||
| Age group (in years) | ||||||
| 15-24 | 4 (22.2) | 28 (39.4) | ||||
| 25-34 | 10 (55.6) | 15 (21.1) | 4.67 (1.25-17.44) | 0.022 | 4.24 (1.02-17.5) | 0.046 |
| 35-44 | 3 (16.6) | 17 (23.9) | 1.24 (0.25-6.21) | 0.79 | 0.99 (0.18-5.65) | 0.99 |
| ≥45 | 1 (5.6) | 11 (15.6) | 0.64 (0.064-6.35) | 0.71 | 0.59 (0.05-6.36) | 0.66 |
| Previous history of treatment | ||||||
| Yes | 6 (33.3) | 6 (8.4) | 5.42 (1.49-19.64) | 0.01 | 6.55 (1.56-27.49) | 0.01 |
| No | 12 (66.7) | 65 (91.6) | ||||
| Smear microscopy | ||||||
| Smear-positive | 12 (66.7) | 46 (64.8) | 1.087 (0.36-3.24) | 0.88 | ||
| Smear-negative | 6 (33.3) | 25 (35.2) | ||||
AOR, Adjusted Odds Ratio; HIV, Human Immunodeficiency Virus; CI, Confidence Interval, COR, Crude Odds Ratio