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. Author manuscript; available in PMC: 2015 Jun 19.
Published in final edited form as: J Pharm Sci. 2012 Apr 26;101(9):3275–3291. doi: 10.1002/jps.23164

Table 2.

The effect of MTX-cIBR on spleen and liver weights at Day 14.

Treatment Rat Spleen Weight ± SE (g) Rat Liver Weight ± SE (g)
Normal + Vehicle 0.2139 ± 0.0060 (100%) * 4.3689 ± 0.1475 (100%) *
Arthritis + Vehicle 0.5823 ± 0.0175 (0%) 6.6191 ± 0.0858 (0%)
Arthritis + 0.05 mg/kg MTX-cIBR 0.4524 ± 0.0139 (35%) * 5.8817 ± 0.0690 (33%) *
Arthritis + 0.2 mg/kg MTX-cIBR 0.4822 ± 0.0248 (27%) 6.1970 ± 0.1721 (19%) **
Arthritis + 1 mg/kg MTX-cIBR 0.4027 ± 0.0202 (49%) * 5.9485 ± 0.1947 (30%) *
Arthritis + 5 mg/kg MTX-cIBR 0.2953 ± 0.017 (78%) * 4.8620 ± 0.2053 (78%) *
Arthritis + 0.05 mg/kg MTX 0.500 ± 0.000 (11%) 6.1289 ± 0.1451 (22%) **
*

p-value < 0.01 when compared to Arthritis + Vehicle.

**

p-value < 0.05 when compared to Arthritis + Vehicle.