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. Author manuscript; available in PMC: 2015 Jun 19.
Published in final edited form as: Psychopharmacology (Berl). 2014 May 15;231(24):4637–4647. doi: 10.1007/s00213-014-3612-4

Figure 2.

Figure 2

Systemic administration of the system xc inhibitor sulfasalazine dose-dependently reduces extracellular glutamate levels in the prefrontal cortex. This graph depicts extracellular glutamate levels in the prefrontal cortex before and after an injection of vehicle (1 ml/kg, IP; N=7) or sulfasalazine (4–16 mg/kg, IP; N= 7–8/group). * p<.05 indicates a significant reduction relative to vehicle-treated subjects in post-injection extracellular glutamate levels in the prefrontal cortex (one-sided Dunnett’s T).

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