Fig. 7.

Impact of the lesion load on DSC, manual lesion load linear correlation with RMNMS, TPR, PPV, LTPR and LPPV. The experiment was conducted with a patch radius of 2 voxels, a search area radius of 5 voxels and a pre-selection of 50 training subjects on the 108 RRMS subjects (represented by colored dots on the graph). The blue line represents a non-parametric fitting using a nearest neighbour approach with a locally weighted regression for DSC, TPR and PPV and a linear fitting for the linear regression of the manual lesion load and RMNMS lesion volume. The darker grey shading represents the 95% confidence and for the linear correlation, the slope, the intercept and the residual error (R²) are provided on the graph.