Sequence alignment of pneumovirus M2-1 proteins. Representative members of pneumoviruses include human metapneumovirus subtype A (hMPV-A; gi 215794520), hMPV-B (gi 215794505), avian metapneumovirus subtype A (aMPV-A; gi 49823139), aMPV-B (gi 310772463), aMPV-C (gi 237847064), human respiratory virus type A (hRSV-A; gi 333959), hRSV-B (gi 2582031), bovine respiratory syncytial virus (BRSV; gi 210823), and pneumonia virus of mice (PVM; GenInfo Identifier [gi] 56900724). Fully conserved residues are highlighted by red boxes, conserved substitutions are indicated by red letters, and black letters mean no match. The dot indicates the number of amino acids. Zinc binding domain (aa 7 to 31) and oligomerization domain (aa 32 to 53) are indicated by an underline. Zinc binding motif (CCCH) is indicated by an arrow.