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. 2015 Apr 1;89(12):6196–6208. doi: 10.1128/JVI.00422-15

FIG 5.

FIG 5

Electrostatic potential calculated for pentameric structures from EV71 VLP, EV71/CVA16 chimeric VLP, and poliovirus types 1 to 3. (A) Electrostatic surface of a pentamer from EV71 VLP, showing strongly negatively charged patches in EV71-SP70 (colored in red, contributed by 213E, 216Q, 217E, 219D, and 221E, all from VP1). Note that the electrostatic potentials calculated by PyMOL (version 1.3r1; Schrödinger, LLC) are crude approximations. (B) A neutral surface is shown in the corresponding SP70 region (colored in white, contributed by 215L, 216Q, 217A, 218N, and 220L) of EV71/CVA16 chimeric VLP. (C) A positively charged surface is shown in the corresponding SP70 region (colored in blue, contributed by 218K, 220Q, 221S, and 222A) of type 1 poliovirus. (D) A rather weakly positively charged surface is shown in the corresponding SP70 region (colored in blue, contributed by 218L, 219G, 220Q, 221A, and 222S) of type 2 poliovirus. (E) A negatively charged surface is shown in the corresponding SP70 region (colored in red, contributed by 217L, 219T, 220D, 221A, and 223D) of type 3 poliovirus.