FIG 8.

Fitting of the EV71 VLP crystal structure into the EM density map. (A) One asymmetric unit in the EV71 VLP crystal structure was represented as ribbons with VP1, VP0, and VP3 colored in magenta, yellow, and cyan, respectively. Amino acids 206 to 217 of VP0 (colored in red) and 212 to 224 of VP1 (colored in green) are both loops near the pseudo-3-fold junction. (B) The cryo-EM density map is colored in blue. The VLP crystal structure is shown in Cα. Some extracontiguous densities are seen ahead of residue 72 of VP1. (C) The cryo-EM density map is colored in blue. The VLP crystal structure is shown in Cα. There are some extracontiguous densities between residues 176 and 190 of VP3.