TABLE 2.

Recombinant JEV mutants bearing PCR-amplified segments of the JEV SA14-14-2 genome

^aMutations at nucleotides indicated with an asterisk were not identified as vaccine strain specific and probably represent differences in the genetic backgrounds of the JEV SA14 and rJEV India/78 wild-type strains.

^bJEV SA14-14-2 PCR-amplified E, NS1/2A, and NS5 gene regions were cloned into the cDNA plasmid of rJEVmut11, which already contained mutations at nucleotides 39, 292, 4403 to 7227, and 10428 (shaded gray), to generate rJEV mutant 14-14-2 (32).

^cBullets indicate that the nucleotide or amino acid is the same as that for rJEV.