TABLE 6.
Immunogenicity of rJEV mutants in weanling mice inoculated by the i.p. route
Virus | Dose (PFU) | No. of mice with seroconversion/total no. of mice | Neutralizing antibody titera (reciprocal EC50) |
|
---|---|---|---|---|
GMT | Range | |||
JEV SA14-14-2 | 104 | 10/10 | 473 | 124–1,026 |
rJEVmut14-14-2 | 104 | 7/10 | 247 | <8–4,556 |
rJEVmutE | 104 | 10/10 | 1,857 | 937–3,736 |
rJEVmut11 | 104 | 10/10 | 1,156 | 496–3,605 |
rJEVmut3 | 104 | 9/9 | 1,361 | 506–2,521 |
Mock | NAb | 0/10 | <8 | <8 |
Geometric mean titer calculated only for seroconverted mice.
NA, not applicable.