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. Author manuscript; available in PMC: 2015 Jun 19.
Published in final edited form as: Cytoskeleton (Hoboken). 2012 Aug 20;69(9):644–658. doi: 10.1002/cm.21057

Figure 2. CdGAP over expression slows random cell migration.

Figure 2

(A) U2OS cells were transfected with GFP or GFP-cdGAP. (B) Representative tracks of transfected U2OS cells plated at low density migrating on 10µg/ml collagen for 16 hours, with GFP-cdGAP transfected cells migrating a shorter distance than GFP control cells. (C) GFP expressing cells migrate at a higher velocity than GFP-cdGAP expressing cells. A minimum of 30 cells from three independent experiments were analyzed per condition and GFP versus GFP-cdGAP expressing cells compared with Student’s t-test,***, p < 0.001. Velocity graph has error bars representing +/− the standard error of the mean.