Table 2.
Quantification of imaging parameters for grade II gliomas (n = 7), grade III gliomas (n = 9) and grade IV (n = 23). p-Values from the Wilcoxon test, values of R2 with significant p-value from a logistic regression analysis between the grade and the parameters (NS: not significant).
Grade II (mean ± SD) | Grade III (mean ± SD) | Grade IV (mean ± SD) | Wilcoxon test (p-value) |
Logistic regression |
||||
---|---|---|---|---|---|---|---|---|
II/III | III/IV | II/IV | R2 | p-Value | ||||
ADCmean (10−6 mm2/s) | 1201 ± 89 | 1345 ± 130 | 1176 ± 129 | NS | 0.013 | NS | 0.04 | NS |
ADCmin (10−6 mm2/s) | 903 ± 66 | 962 ± 55 | 837 ± 71 | NS | <0.001 | NS | 0.15 | <0.01 |
rCBVmean | 1.18 ± 0.19 | 1.11 ± 0.35 | 1.59 ± 0.43 | NS | 0.010 | 0.035 | 0.15 | <0.01 |
rCBVmax | 1.88 ± 0.37 | 1.77 ± 0.52 | 2.73 ± 0.68 | NS | <0.01 | 0.013 | 0.21 | <0.001 |
Cho/Cr | 1.41 ± 0.20 | 3.71 ± 4.04 | 3.65 ± 1.97 | 0.03 | NS | <0.01 | 0.03 | NS |
NAA/Cr | 1.15 ± 0.28 | 0.85 ± 0.40 | 0.89 ± 0.33 | NS | NS | NS | 0.01 | NS |
Cho/NAA | 1.18 ± 0.41 | 4.91 ± 4.66 | 3.84 ± 2.44 | NS | NS | 0.021 | 0.01 | NS |
FLTmean (g/ml) | 0.27 ± 0.09 | 0.25 ± 0.09 | 0.61 ± 0.23 | NS | <0.001 | <0.01 | 0.36 | <0.0001 |
FLTmax (g/ml) | 0.34 ± 0.09 | 0.33 ± 0.14 | 1.27 ± 0.56 | NS | <0.0001 | <0.001 | 0.5 | <0.0001 |