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. 2015 May 29;8:448–454. doi: 10.1016/j.nicl.2015.05.012

Table 2.

Quantification of imaging parameters for grade II gliomas (n = 7), grade III gliomas (n = 9) and grade IV (n = 23). p-Values from the Wilcoxon test, values of R2 with significant p-value from a logistic regression analysis between the grade and the parameters (NS: not significant).

Grade II (mean ± SD) Grade III (mean ± SD) Grade IV (mean ± SD) Wilcoxon test (p-value)
Logistic regression
II/III III/IV II/IV R2 p-Value
ADCmean (10−6 mm2/s) 1201 ± 89 1345 ± 130 1176 ± 129 NS 0.013 NS 0.04 NS
ADCmin (10−6 mm2/s) 903 ± 66 962 ± 55 837 ± 71 NS <0.001 NS 0.15 <0.01
rCBVmean 1.18 ± 0.19 1.11 ± 0.35 1.59 ± 0.43 NS 0.010 0.035 0.15 <0.01
rCBVmax 1.88 ± 0.37 1.77 ± 0.52 2.73 ± 0.68 NS <0.01 0.013 0.21 <0.001
Cho/Cr 1.41 ± 0.20 3.71 ± 4.04 3.65 ± 1.97 0.03 NS <0.01 0.03 NS
NAA/Cr 1.15 ± 0.28 0.85 ± 0.40 0.89 ± 0.33 NS NS NS 0.01 NS
Cho/NAA 1.18 ± 0.41 4.91 ± 4.66 3.84 ± 2.44 NS NS 0.021 0.01 NS
FLTmean (g/ml) 0.27 ± 0.09 0.25 ± 0.09 0.61 ± 0.23 NS <0.001 <0.01 0.36 <0.0001
FLTmax (g/ml) 0.34 ± 0.09 0.33 ± 0.14 1.27 ± 0.56 NS <0.0001 <0.001 0.5 <0.0001