Table 3.
Top 10 ranked cardiovascular diseases and its related risk factors.
| Diseases/traits Based on GWAS genetics (878) | Diseases Based on OMIM genetics (4732) | ||
|---|---|---|---|
| Diseases/traits | Ranking (top%) |
Diseases | Ranking (top%) |
| Obesity-related traits | 0.11% | Myocardial infarction, susceptibility to | 0.23% |
| Coronary heart disease | 0.80% | Ventricular tachycardia | 0.25% |
| HDL cholesterol | 1.13% | Diabetes mellitus, noninsulin-dependent | 0.32% |
| Type 2 diabetes | 1.48% | Coronary artery disease, susceptibility to | 0.51% |
| LDL cholesterol | 1.82% | LDL cholesterol level qt | 0.66% |
| Total cholesterol | 1.94% | Hypercholesterolemia, familial | 0.68% |
| Triglycerides | 3.30% | Microvascular complications of diabetes | 0.69% |
| Lipid metabolism phenotypes | 3.53% | Atherosclerosis, susceptibility to | 0.78% |
| Metabolic syndrome | 3.64% | Obesity, susceptibility to | 1.88% |
| Cardiovascular disease risk factors | 4.55% | Diabetes mellitus, type 2, susceptibility to |
3.14% |