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. Author manuscript; available in PMC: 2016 Jul 1.
Published in final edited form as: Am J Transplant. 2015 Feb 27;15(7):1768–1781. doi: 10.1111/ajt.13189

Figure 8. Cyclosporine and elafin synergistically promote airway microvascular perfusion and oxygenation.

Figure 8

(A) FITC-lectin perfusion image showing that neither elafin (1.9mg/kg/d) nor CsA (2.5mg/kg/d) is able to preserve microvascular circulation of d10 allografts, but the combination of elafin and CsA therapy protects the microvascular circulation. (B) Quantification of perfused area. (C, D) Both blood perfusion unit study (C) and tissue pO2 examination (D) showed the synergistic effect of elafin and CsA (n=4–6 per group). Scale bar, 100μm (A). Data are shown as mean±SEM. Student’s t test was used to compare groups. *P<0.05.