Table 2. Top Ethnicity-Stratified Single-SNP Association Results, Adjusted for Age, Sex, BMI, Smoking, and First Three PCs.
| SNP | Gene | Chr | Position | Ethnicity | MAF | Ref/Alt | Protein | Beta | SE | P |
|---|---|---|---|---|---|---|---|---|---|---|
| rs5745687 | HGF | 7 | 81359051 | EUR | 0.073 | A/G | p.E299K | −85.7 | 12.5 | 7.83E-12 |
| rs200231675* | DPH1 | 17 | 1944781 | CHN | 0.007 | G/C | p.V370L | 323.9 | 62.4 | 2.68E-07 |
| rs57257204* | NOTCH2 | 1 | 120500640 | HIS | 0.064 | G/A | Intron | 93.2 | 18.6 | 5.77E-07 |
| rs7163763* | CHRNA7 | 15 | 31822215 | AFA | 0.017 | T/A | Intron | 157.7 | 32.2 | 1.04E-06 |
AFA, African American; CHN, Chinese American; EUR, European American; HIS, Hispanic American; MAF, minor allele frequency; SE, standard error
*
Not statistically significant at α = 1.95E-07