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. Author manuscript; available in PMC: 2016 Jul 1.
Published in final edited form as: Ann Hum Genet. 2015 May 22;79(4):264–274. doi: 10.1111/ahg.12119

Table 3. Significant single-SNP trans-ethnic meta-analysis results.

Stratified Analysis P (MAF) Meta-Analysis Cochran’s Q


SNP Gene Chr Position AFA CHN EUR HIS Ref/Alt Protein Beta SE P Stat P
rs5745687 HGF 7 81359051 3.1E-04
(0.014)
NA*
(0.001)
7.8E-12
(0.073)
3.0E-04
(0.042)
A/G p.E299K −89.1 10.5 2.88E-17 1.43 0.49
rs16844364 RGS12 4 3438643 0.014
(0.129)
0.001
(0.451)
0.045
(0.225)
2.7E-06
(0.275)
G/C Intron 29.7 4.9 1.98E-09 6.58 0.09
rs4690098 HGFAC 4 3447156 0.771
(0.056)
0.007
(0.445)
5.3E-05
(0.226)
8.4E-04
(0.230)
T/C Intron −28.8 5.2 3.22E-08 4.16 0.24
rs114303452 HGFAC 4 3449915 NA*
(0.002)
NA*
(0.000)
2.9E-06
(0.017)
3.4E-03
(0.005)
G/A p.K566R 125.5 23.1 5.85E-08 1.07 0.30
rs3748034 HGFAC 4 3446091 0.346
(0.046)
0.007
(0.308)
0.005
(0.144)
9.7E-05
(0.127)
C/A p.A218S 32.2 6.1 1.11E-07 3.20 0.36

AFA, African American; CHN, Chinese American; EUR, European American; HIS, Hispanic American; MAF, minor allele frequency; SE, standard error

*

Stratified analysis results not available for meta-analysis due to low empirical MAF.

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